← brief for 2026-08-31 · Slowing decline
Efficacy and safety of henagliflozin in IgA nephropathy: A real-world observational study from China.
Key takeaways
In 48 Chinese adults with IgA nephropathy, henagliflozin — a new SGLT2 inhibitor — lowered protein in the urine by about 35% after 12 weeks, and side effects were mild. This observational study shows a link between the drug and less protein in urine, but it does not prove cause-and-effect because there was no comparison group.
Who did this work
Zhang YQ · Wu JX · Tu HY · Ren ZT · Chen PP · Zhang JX · Ma KL
Source
Article · PubMed, the drug frontier · 2026 Aug 31
https://pubmed.ncbi.nlm.nih.gov/42670683/