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← brief for 2026-08-31 · Slowing decline

Efficacy and safety of henagliflozin in IgA nephropathy: A real-world observational study from China.

Article C Peer reviewed Observational

Key takeaways

In 48 Chinese adults with IgA nephropathy, henagliflozin — a new SGLT2 inhibitor — lowered protein in the urine by about 35% after 12 weeks, and side effects were mild. This observational study shows a link between the drug and less protein in urine, but it does not prove cause-and-effect because there was no comparison group.

Who did this work

Zhang YQ · Wu JX · Tu HY · Ren ZT · Chen PP · Zhang JX · Ma KL

Source

Article · PubMed, the drug frontier · 2026 Aug 31
https://pubmed.ncbi.nlm.nih.gov/42670683/