← brief for 2026-08-19 · Slowing decline

Urea transporter B-mediated urea uptake-induced protein carbamylation in platelets underlies bleeding in chronic kidney disease.

Article D Peer reviewed Preclinical

Key takeaways

This study in mice found that urea transporter B (UT-B) in platelets causes bleeding in CKD. The results suggest a link between UT-B and bleeding risk, but human trials are needed.

Who did this work

Qiu Z · Xiong F · Wang Z · Zhao Y · Gao S · Zhang X · Chen Y · Liu Z · Li R · Cao L · Sun L · Shao G

Source

Article · PubMed, CKD severity and reversal · 2026 Aug 19
https://pubmed.ncbi.nlm.nih.gov/42616841/