← brief for 2026-08-19 · Slowing decline

Mitochondrial Dysfunction in Ifosfamide-Induced Nephrotoxicity: Mechanisms and Possible Interventions.

Key takeaways

This is a review of how a chemotherapy drug called ifosfamide can harm the kidneys, so it reports no new results. The damage seems to come from injury to mitochondria, the tiny power plants inside kidney cells. This kind of kidney injury can lead to long-term kidney disease. The authors go over the causes and possible ways to protect the kidneys.

Who did this work

Liang K · Ciapaite J · Masereeuw R · Verhaar MC · van den Heuvel-Eibrink MM · Slaats GG · van den Berg G

Source

Article · PubMed, CKD progression and prevention · 2026 Aug 19
https://pubmed.ncbi.nlm.nih.gov/42617903/