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Response to: “Matters arising: effect modification by chronic kidney disease on renal outcomes in septic shock patients undergoing high-MAP targeting: a secondary analysis of the OPTPRESS trial”

Key takeaways

This paper discusses the debate over blood pressure targets in septic shock patients with CKD. It addresses how-to use MAP (mean arterial pressure) targets to avoid kidney injury.

Who did this work

Hiraaki Okuzawa (Tsuchiura Kyodo General Hospital) · Akira Endo (Hokkaido University)

Source

Paper · OpenAlex, CKD works · 2026-08-14
https://doi.org/10.1186/s40560-026-00914-2