Decline is not inevitable.
A daily, evidence-graded view of everything moving in kidney research : the drugs that slow decline, the science of regeneration, and the mind-body work.
New review confirms semaglutide helps protect your heart and kidneys.
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Most other reports today are small studies or early data that do not yet prove cause and effect.
The strongest news today is a review confirming that semaglutide offers benefits for the heart, kidneys, and liver. This evidence comes from large studies with many participants. Other items are mostly smaller studies or early reports that show links but not proof. The day is shaped by solid data on diabetes drugs and observational links in transplant care.
Semaglutide As a Multiorgan Therapeutic Agent: Evidence for Cardiovascular, Renal, and Hepatic Benefits
This review summarizes large trials of semaglutide, a diabetes drug. It shows the drug slows kidney decline and protects the heart. It also helps with liver health. The evidence comes from big studies with many people.
Twenty-four-hour proteinuria and acute kidney injury in women with preeclampsia in Peru
This study looked at 127 women with a pregnancy condition called preeclampsia. It checked if high protein in the urine linked to sudden kidney injury. It shows a link, but not proof of cause.
Renin-angiotensin system inhibitors and arterial stiffness in chronic kidney disease: results from the chronic renal insufficiency cohort.
This study tracked people with kidney disease to see if common blood pressure drugs kept their arteries flexible. It shows a link between the drugs and artery stiffness, but not proof of cause.
Acute Renal and Hemodynamic Risk in Young Adults With Sickle-Cell Trait and Disease: A Propensity-Score-Matched Analysis.
This study compared young adults with sickle-cell disease to those without it. It looked at sudden kidney and blood flow problems. It shows a link to higher risk, but not proof of cause.
Allopurinol underdosage in Danish primary care: a 2-year cohort study of patients with gout, including those with chronic kidney disease
This study looked at people in Denmark who have gout and kidney disease. It found that many of them were not taking the full dose of allopurinol, a drug that lowers uric acid. The study shows a link between low doses and kidney issues, but it does not prove that the low dose caused the problems. This is important because the right dose helps prevent severe joint damage.
Faktor yang Memengaruhi Kualitas Tidur Pasien Gagal Ginjal Kronik
This study asked 83 dialysis patients about their sleep. It found that itching and anxiety hurt sleep quality. It shows a link, but not proof of cause.
Pre-existing heart failure subtype and in-hospital mortality in liver transplantation: a nationwide analysis
This study looked at records of people who had liver transplants. It checked if having heart failure changed the chance of dying in the hospital. It also looked at kidney injury. This is an observational study, so it shows a link, not proof of cause.
Combined assessment of serum netrin-1 and GDF-15 across albuminuria stages in type 2 diabetes
This study looked at blood markers in 60 people with type 2 diabetes. It checked if these markers could spot early kidney damage. The study shows a link between these markers and kidney health. It is an observational study, so it does not prove cause and effect.
Pre-transplant cardiovascular risks and adverse outcomes in patients after receiving kidney transplantation
This study followed 3,562 people who got a kidney transplant. It looked at heart risks before the surgery. The follow-up lasted about 7.7 years on average. It shows a link between heart risks and bad outcomes, but it is not proof of cause.
Ferroptosis in podocyte injury in diabetic kidney disease: mechanisms and therapeutic perspectives
This review explains how a type of cell death called ferroptosis harms kidney cells in diabetes. It discusses how high sugar and fats trigger this process. This is a review of lab and animal studies, not people yet.
Integrative network toxicology and single-nucleus transcriptomics reveal molecular overlap between predicted 6PPD-quinone targets and diabetic kidney disease
This study used computer models to look at a chemical from tires. It checked if this chemical might affect kidney cells. The work was done in data sets and models, not in people. It suggests a possible link that needs more testing.
Finerenone Demonstrates Superior Renoprotective and Anti-Fibrotic Efficacy over Eplerenone in Diabetic Nephropathy Rats
This test was done in rats, not people. It compared two drugs to see which one better protected the kidneys from scarring. The new drug, finerenone, worked better than the older one in these animals.
TCT-626 Comparative Effectiveness of Contemporary Pharmacologic Therapies and Renal Denervation for Resistant Hypertension: A Systematic Review and Network Meta-analysis
This is a review of studies comparing a nerve procedure to new blood pressure drugs. It looks at people whose blood pressure is hard to control. There are no results yet from this specific paper.
Childhood Food Insecurity and the Development of Atherosclerotic Cardiovascular Disease: Dietary, Metabolic, and Psychosocial Pathways
This paper discusses how not having enough food in childhood affects heart health later. It is a review of existing knowledge. There are no new results from this specific paper.
Biopsy-Proven Renal AA Amyloidosis Revealing Underlying Pulmonary Tuberculosis With the Kidney as an Innocent Bystander: A Case Report and Literature Review
This is a report on one patient whose kidney disease came from an old lung infection. It is a single case, so it does not show a general rule. There are no broad results yet.
Brain activity characteristics of chronic kidney disease-associated pruritus in maintenance hemodialysis patients: a resting-state fMRI study
This study used brain scans to look at itching in people on dialysis. It is a new paper, so there are no results yet to report.
TCT-1376 Contemporary Trends, Clinical Characteristics, and One-Year Outcomes Following Renal Denervation: A Real-World Analysis of 540 Patients from TriNetX
This is a conference abstract about a procedure that uses energy to treat high blood pressure. It looks at 540 patients. The full study details are not available in this record. There are no results to report from this specific entry.
TCT-116 Trends in Mortality From Infective Endocarditis with Concomitant Chronic Kidney Disease in the United States, 1999–2024: A 26-Year Population-Based Analysis
This abstract looks at death rates from a heart infection over 26 years. It focuses on people who also have kidney disease. The full data is not included in this record. There are no results to report from this specific entry.
TCT-1179 Renal Function Trajectory and Cardiac Structural Remodeling in Patients After Percutaneous Coronary Intervention: A Large Real-World Cohort Study
This abstract looks at how kidney function changes after heart procedures. It focuses on patients who had a stent placed. The full study details are not available in this record. There are no results to report from this specific entry.
TCT-298 Impact of Kidney Disease on Outcomes After Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis for Pulmonary Embolism: A National Inpatient Sample Analysis
This abstract compares two treatments for a blood clot in the lung. It looks at how kidney disease affects the results. The full data is not included in this record. There are no results to report from this specific entry.