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← brief for 2026-11-01 · Slowing decline

Chronic kidney disease and blood-based biomarkers of Alzheimer's disease: the brain in kidney disease study.

Article C Peer reviewed Observational

Key takeaways

This study checked blood samples from 443 people with kidney disease. It found that lower kidney function was linked to higher levels of a brain protein. This is an observational study, so it shows a link, not proof of cause. It suggests kidney health may affect brain health markers.

Who did this work

Sheets KM · Curran JM · Mielke MM · Zeng X · Karikari TK · Sutphen CL · Register TC · Murray AM

Source

Article · PubMed, CKD progression and prevention · 2026 Oct
https://pubmed.ncbi.nlm.nih.gov/42967588/