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Allopurinol underdosage in Danish primary care: a 2-year cohort study of patients with gout, including those with chronic kidney disease

Article C Peer reviewed Observational

Key takeaways

This study looked at people in Denmark who have gout and kidney disease. It found that many of them were not taking the full dose of allopurinol, a drug that lowers uric acid. The study shows a link between low doses and kidney issues, but it does not prove that the low dose caused the problems. This is important because the right dose helps prevent severe joint damage.

Who did this work

Claus Rasmussen (North Denmark Region) · Jesper Walther Larsen (North Denmark Region) · Terpager Jepsen (North Denmark Region) · Christian Holstein Raun (Aalborg University Hospital) · Peter Derek Christian Leutscher (North Denmark Region)

Source

Article · OpenAlex, CKD works · 2026-10-31
https://doi.org/10.1186/s12875-026-03640-8