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Effects of sodium-glucose cotransporter 2 inhibitors on the kidneys: a pharmacovigilance study and genetic causal analysis

Article C Peer reviewed Observational

Key takeaways

This study checked real-world reports of kidney injury from SGLT2 inhibitors. It used genetic data to look for a cause. It suggests the drugs are generally safe, but this is an observational link, not proof from a trial.

Who did this work

Zhiwang Lai (Fujian Medical University) · Huan Ye (Fujian Medical University) · Jiayuan Lai (Fujian Medical University) · Junyao Lin (Guangxi University of Chinese Medicine) · Hongjin Gao (Fujian Medical University)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-30
https://doi.org/10.1186/s43162-026-00753-5