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← brief for 2026-10-31 · Slowing decline

Effect of Melatonin on 24-Hour Urinary Protein Excretion and Sleep Quality in Patients With Stage 3-4 Chronic Kidney Disease: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Article B Peer reviewed Small trial

Key takeaways

This study tested melatonin in adults with stage 3-4 kidney disease. It ran for 12 weeks and compared the supplement to a placebo. The goal was to see if melatonin lowers protein in the urine. Protein in the urine is a sign of kidney damage. The text does not list the total number of people in the trial. It also does not state the final results of the test.

Who did this work

Ziaie S · Mahdavi B · Pourrezagholi F · Niri AN · Abbasinazari M · Asadpour R

Source

Article · PubMed, CKD progression and prevention · 2026 Oct 29
https://pubmed.ncbi.nlm.nih.gov/42964503/