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Mesenchymal stem cell-derived exosomes alleviate renal interstitial fibrosis via pVHL-mediated HIF-1α ubiquitination and degradation

Article D Peer reviewed Preclinical

Key takeaways

This study tested tiny particles from stem cells in cells and animals. The particles helped reduce scarring in the kidney. This was done in a lab setting, not in people yet.

Who did this work

Chen Qi (Suzhou Municipal Hospital) · Bei Li (Jiangsu University) · Wei Wu (Qinghai University for Nationalities) · Linru Shi (Jiangsu University) · Xianbin Xia (Xinyu University) · Cheng Ji (Jiangsu University)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-24
https://doi.org/10.1186/s12915-026-02766-6