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← brief for 2026-10-25 · Nutrition & lifestyle

Dietary sodium intake and kidney tubular protein abundance in urinary extracellular vesicles.

Preprint B Not peer reviewed Small trial

Key takeaways

Forty-six healthy adults with normal kidney function tried a very low salt diet, then a high salt diet. The study measured proteins in their urine to see how the kidneys handled salt. It found that salt intake changed the amount of certain kidney proteins. This was a small test, so the results need more study to be sure.

Who did this work

Claudel SE · Mahrokhian S · Hanna I · Newman AJ · Brown J · Verma A · Waikar SS · Auchus RJ · McDonald WH · Schey KL · Peng D · Luther JM

Source

Preprint · PubMed, the drug frontier · 2026 Oct 6
https://pubmed.ncbi.nlm.nih.gov/42926846/