← brief for 2026-10-22 · Slowing decline

Single-cell transcriptomic analysis of the terminal ileum identifies BCMA as a therapeutic target in IgA nephropathy.

Article D Peer reviewed Preclinical

Key takeaways

Scientists looked at cells from the gut and blood of people with IgA nephropathy. They found a specific target called BCMA that might help treat the disease. This work was done in cells and samples, not in a full human trial yet. It points to a new way to fight this kidney disease.

Who did this work

Zhang Y · Wang L · Wu J · Wan N · Liu X · Lin M · Li J · Wang J · Wu J · Peng J · Dang S · Xie T

Source

Article · PubMed, CKD progression and prevention · 2026 Feb 12
https://pubmed.ncbi.nlm.nih.gov/42903470/