← brief for 2026-10-22 · Slowing decline

Neutralization of the PTX3 / CD44 axis suppresses TGF ‐β1 signaling in kidney fibrosis

Article D Peer reviewed Preclinical

Key takeaways

This study in mice showed that blocking a specific protein can reduce kidney scarring. The protein helps trigger the scarring process. This was in animals, not people yet.

Who did this work

Chao‐Chun Cheng (National Cheng Kung University) · Shen‐Shin Chang (National Cheng Kung University Hospital) · Feng‐Wei Chen (National Cheng Kung University) · Ying‐Chieh Su (Chi Mei Medical Center) · Thanh Phuong Nguyen (National Cheng Kung University) · Yu‐Wei Hsiao (National Cheng Kung University) · Jhih‐Ying Chi (National Cheng Kung University) · Hsin‐Yin Liang (National Cheng Kung University) · Ju‐Ming Wang (Kaohsiung Medical University)

Source

Article · OpenAlex, CKD works · 2026-10-21
https://doi.org/10.1002/1873-3468.70480