← brief for 2026-10-22 · Slowing decline

Genetically determined metabolite variation identifies a heat related pathway in workers at risk of Mesoamerican Nephropathy

Article No results yet Peer reviewed

Key takeaways

This study looks at urine samples from workers in Nicaragua who are at risk for a specific type of kidney disease. It finds links between genes, heat, and kidney injury. It is an observational study, so it shows a connection but not proof of cause.

Who did this work

Dominick A. Leone (Boston University) · Nathan H. Raines (Beth Israel Deaconess Medical Center) · Juan Jose Amador (Boston University) · Iris Delgado (Boston University) · Nieves Embade (CIC bioGUNE) · Rubén Gil‐Redondo (CIC bioGUNE) · Cristina O’Callaghan Gordo (Universitat Oberta de Catalunya) · Jessica H. Leibler (Boston University) · Damaris López-Pilarte (Hospital Punta Pacifica) · Óscar Millet (CIC bioGUNE) · Achilleas Pitsillides (Boston University) · Oriana Ramírez‐Rubio (Barcelona Institute for Global Health)

Source

Article · OpenAlex, CKD works · 2026-10-20
https://doi.org/10.1038/s41598-026-76047-1