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Silencing of RAB3A Reshapes the Extracellular Vesicle ncRNA Landscape in Diabetic Podocytes and Uncovers miR-126-3p as a Candidate Mediator of Podocyte Injury

Key takeaways

This research used kidney cells in a lab to study how diabetes causes damage. It looked at tiny bubbles that cells release to talk to each other. This work was done in cells, not in people yet. It helps find new targets for future drugs.

Who did this work

Olga Martínez-Arroyo (INCLIVA Health Research Institute) · Ana Flores-Chova (INCLIVA Health Research Institute) · Lesley Escrivá (INCLIVA Health Research Institute) · Sergio Martínez‐Hervás (Universitat de València) · Cristina Grange (University of Turin) · Benedetta Bussolati (University of Turin) · María José Forner (Universitat de València) · Josep Redón (Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition) · Raquel Cortés (Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas) · Ana Ortega (Centro de Investigación en Red en Enfermedades Cardiovasculares)

Source

Article · OpenAlex, CKD works · 2026-10-08
https://doi.org/10.3390/biom16101466