← brief for 2026-10-09 · Regeneration & devices

PolyCore, a bimodal peritoneal dialysis solution based on xylitol, L-carnitine, and icodextrin: In vitro evidence of the peritoneal membrane protection, rationale, and design of the phase II pilot study EXCITE

Article D Peer reviewed Preclinical

Key takeaways

A new dialysis fluid called PolyCore was tested on human cells in a lab. It helped protect the cells from damage. This was not a test in people yet.

Who did this work

Silvio Borrelli (University of Campania "Luigi Vanvitelli") · Valentina Masola (University of Padua) · Tommaso Prosdocimi · Richard Corbett (Imperial College Healthcare NHS Trust) · Francesco Trepiccione (Biogem) · Lorenzo Di Liberato (University of Chieti-Pescara) · Mario Bonomini (University of Chieti-Pescara) · Gaetano La Manna · Giacomo Magnoni · Luca Nardelli (Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia) · Giuseppe Castellano (University of Milan) · Giuseppe Paribello (Federico II University Hospital)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-08
https://doi.org/10.1177/08968608261493817