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← brief for 2026-10-09 · Nutrition & lifestyle

Inhibition of xanthine oxidase protects against heatstroke-related acute kidney injury.

Article D Peer reviewed Preclinical

Key takeaways

This study tested if a gout drug called febuxostat protects kidneys from heatstroke. The researchers used kidney cells in a lab and mice in a cage. The drug seemed to reduce kidney damage in the mice. This work was done in animals and cells, not people yet.

Who did this work

Chen W · Song Y · Jia Y · Xiao F · Zhang M · Lan C · Yang X · Wang L · Dai H

Source

Article · PubMed, Climate, heat and the kidney · 2026 Oct 8
https://pubmed.ncbi.nlm.nih.gov/42850762/