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Hyperglycemia Drives an Activated, Lipid-Laden Nonclassical Monocyte Phenotype in Diabetes

Article D Peer reviewed Preclinical

Key takeaways

This study looked at blood cells in the lab. It found that high blood sugar changes how these cells handle fats. This was done in cells, not in people yet. It helps explain how diabetes might hurt kidneys.

Who did this work

Jocelyn Cervantes (University of Washington) · Anika Consul (University of Washington) · Alan Tran (University of Washington) · Jingjing Tang (University of Washington) · Farah Kramer (University of Washington) · Huaqing Zheng (University of Washington) · Adam E. Mullick (Ionis Pharmaceuticals (United States)) · Tomáš Vaisar (University of Washington) · Francis Kim (University of Washington) · Karin Bornfeldt (University of Washington) · Baohai Shao (University of Washington) · Jenny E. Kanter (University of Washington)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-08
https://doi.org/10.2337/db26-0085