← brief for 2026-10-08 · Slowing decline

Intensive vs Standard Blood Pressure Lowering in People With and Without Chronic Kidney Disease

Key takeaways

A large review of many trials found that lowering blood pressure aggressively helps protect kidneys. This is true for people with and without chronic kidney disease. The study looked at hard outcomes like kidney failure and heart disease. It confirms that strict blood pressure control is a key way to slow kidney decline.

Who did this work

Fotini Iatridi (Aristotle University of Thessaloniki) · Alistair Roddick (Churchill Hospital) · Natalie Staplin (University of Oxford) · Zhaojing Che (University of Oxford) · Jiamin Liu (Chinese Academy of Medical Sciences & Peking Union Medical College) · Ryoki Arimoto (Churchill Hospital) · Abdulrahman Al-Mohammad (University of Oxford) · Yan Li (Chinese Academy of Medical Sciences & Peking Union Medical College) · Jinzhuo Ge (Chinese Academy of Medical Sciences & Peking Union Medical College) · Elaine Ku (University of California, San Francisco) · Mark J. Sarnak (Tufts Medical Center) · Marieta P. Theodorakopoulou (Aristotle University of Thessaloniki)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-07
https://doi.org/10.1001/jamacardio.2026.4445