← brief for 2026-10-06 · Slowing decline

The role and mechanism of macrophage-to-myofibroblast transition in fibrotic diseases

Article D Peer reviewed Preclinical

Key takeaways

This review explains how a type of immune cell can turn into a scar-making cell. This process is called macrophage-to-myofibroblast transition. It is a key step in how kidney tissue gets stiff and scarred. The work is based on lab studies, not people yet.

Who did this work

Hua Guo (First Affiliated Hospital of Guangzhou Medical University) · Xiao Xiao Tang (First Affiliated Hospital of Guangzhou Medical University)

Source

Article · OpenAlex, CKD works · 2026-10-05
https://doi.org/10.3389/fimmu.2026.1919029