← brief for 2026-10-04 · Transplant & xeno

Single-cell multi-omics characterization of rejection in transplanted kidneys reveals key cell types and candidate regulators of chronic rejection

Key takeaways

This study used a mouse model to look at cells in transplanted kidneys. It found specific cell types involved in chronic rejection. This was in animals, not people yet.

Who did this work

Bingxuan Zheng (First Affiliated Hospital of Xi'an Jiaotong University) · Junbo Li (Chinese Academy of Medical Sciences & Peking Union Medical College) · Qi He (First Affiliated Hospital of Xi'an Jiaotong University) · Zepeng Li (First Affiliated Hospital of Xi'an Jiaotong University) · Tian Wei (First Affiliated Hospital of Xi'an Jiaotong University) · Yang Gao (First Affiliated Hospital of Xi'an Jiaotong University) · Yanan Zhu (First Affiliated Hospital of Xi'an Jiaotong University) · Ge Deng (First Affiliated Hospital of Xi'an Jiaotong University) · Mei Yang (First Affiliated Hospital of Xi'an Jiaotong University) · Puxun Tian (First Affiliated Hospital of Xi'an Jiaotong University) · Chenguang Ding (First Affiliated Hospital of Xi'an Jiaotong University)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-03
https://doi.org/10.1186/s12967-026-09002-3