← brief for 2026-10-04 · Slowing decline

Leucine Mitigates Diabetic Nephropathy via Its Antioxidant Effect and Modulation of TGF-β/SMAD-3 Signalling Pathway in Streptozotocin-Induced Diabetic Rats.

Key takeaways

This study gave a protein called leucine to 40 rats with diabetes. The rats that got leucine had less kidney damage than those that did not. This was done in animals, not people yet.

Who did this work

Merdas ZJH (Department of Pharmacology & Toxicology, College of Pharmacy, Amman Arab University, Amman, Jordan.) · Bekhit MA (Egypt Healthcare Authority, Comprehensive Health Insurance, Ismailia, Egypt.) · Hazem RM (Department of Pharmacology & Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.) · Gad ES (Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsaa, Saudi Arabia.) · Al Qtaish N (Department of Pharmacology & Toxicology, College of Pharmacy, Amman Arab University, Amman, Jordan.) · Alsumait AF (Clinical Nutrition Department, Kuwait Cancer Control Center, Ministry of Health, Kuwait City, Kuwait.) · El-Sayed NM (Department of Pharmacology & Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.)

Source

Article · Europe PMC, CKD · 2026-09-28
https://doi.org/10.2147/dddt.s619144