← brief for 2026-10-04 · Regeneration & devices

Kidney-directed AAV9 Klotho gene delivery improves renal function in a mouse model of chronic kidney disease.

Article D Peer reviewed Preclinical

Key takeaways

This study used a gene therapy to deliver a protein called Klotho to the kidneys of mice. The mice had a model of chronic kidney disease. This was done in animals, not people yet.

Who did this work

Yan C · Jian L

Source

Article · PubMed, Reducing protein and albumin in urine · 2026 Oct 1
https://pubmed.ncbi.nlm.nih.gov/42829956/