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Whole-genome sequencing characterizes monogenic and polygenic contributions to structural kidney and urinary tract malformations

Key takeaways

This study used full gene tests to look at children with kidney birth defects. It found that many of these defects come from multiple genes working together. This shows a link between genes and the condition, but it is not proof of cause.

Source

Paper · Kidney International · 2026-09-20
https://www.kidney-international.org/article/S0085-2538(26)00790-8/fulltext?rss=yes