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Emerging genetic mechanisms of glomerular proteinuria: a podocyte-centered multi-layer network perspective

Article A Peer reviewed Meta-analysis or large trial

Key takeaways

This review summarizes many studies on genes that cause protein to leak into urine. It focuses on podocytes, which are cells in the kidney that act as filters. The review finds that damage to these cells is a main driver of kidney disease. It maps how different genes affect these cells to help explain why kidneys fail.

Who did this work

Meijia Fu (Academy of Medical Sciences) · Jiayi Lin (Academy of Medical Sciences) · Cong Wang (Shandong Provincial Hospital) · Xiaoyuan Wang (Shandong Provincial Hospital)

Source

Article · OpenAlex, CKD works · 2026-09-20
https://doi.org/10.3389/fgene.2026.1934937