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Characterization of the neoprotein MUC1-fs in patient-derived cells with ADTKD-MUC1

Preprint D Not peer reviewed Preclinical

Key takeaways

ADTKD-MUC1 is an inherited kidney disease that often leads to kidney failure in middle age. A faulty gene makes an abnormal protein called MUC1-fs, and it builds up in kidney tube cells. Researchers grew kidney cells taken from patients' urine so they could study how this protein is made and controlled. This work was done in cells in the lab, not in people, and it has not been peer reviewed yet.

Source

Preprint · medRxiv nephrology preprints · 2026-09-16
https://www.medrxiv.org/content/10.64898/2026.09.16.26363125v1?rss=1