← brief for 2026-09-17 · Transplant & xeno

C-Reactive Protein as a Biomarker of Inflammation and Graft Injury After Kidney and Heart Allo- and Xenotransplantation Into Non-Human Primates.

Key takeaways

Researchers tested whether C-reactive protein (CRP), a common blood marker of inflammation, can signal when a transplanted organ is being rejected. They studied 42 baboons and monkeys that got kidney or heart transplants, including organs from pigs (xenotransplants). They also looked at CRP rises that happened without clear harm to the organ, and compared the two monkey species. This was done in animals, not people yet, so it cannot tell us how well CRP works for human transplant patients.

Who did this work

Zaletel T · Elias GF · Habibabady Z · Dufault M · Kinoshita K · Otsuka R · Kuravi K · Ayares D · Whitworth KM · Hall K · Kawai T · Madsen JC

Source

Article · PubMed, xeno · 2026 Sep-Oct
https://pubmed.ncbi.nlm.nih.gov/42750217/