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Mean Platelet Volume and Mean Platelet Volume-to-Platelet Ratio and Their Association With Mortality in Patients Undergoing Maintenance Hemodialysis

Key takeaways

Platelets are the blood cells that form clots, and routine blood tests already report their average size. This study checked whether that size, and the ratio of size to platelet count, tracked with the risk of dying in people on long-term hemodialysis. Both are cheap numbers that show up on a standard blood count, so a real signal would be easy to use in the clinic. It is an observational study, so it shows a link with survival, not proof that platelet size causes death.

Who did this work

Nenova D (Department of Nephrology, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR) · Yankov Y (Clinic of Maxillofacial Surgery, University Hospital "St. Marina", Varna, BGR) · Chausheva G (Department of Clinical Laboratory, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR)

Source

Paper · Europe PMC, CKD · 2026-09-14
https://europepmc.org/article/PMC/PMC13571475