← brief for 2026-09-14 · People & money

Preoperative renin-angiotensin system inhibitor management and acute kidney injury after cardiac surgery: a systematic review and meta-analysis

Paper A Peer reviewed Meta-analysis or large trial

Key takeaways

A large review of many studies found that stopping renin-angiotensin system inhibitors (like lisinopril or losartan) before heart surgery raises the risk of sudden kidney injury by about 40% compared to continuing them. This holds true across over 15,000 patients and supports keeping these blood pressure drugs going through surgery to protect the kidneys.

Who did this work

Manli Huang · Zefei Zhang · Yue Zhang · Baobao Gao · Xue Yang · Lini Wang · Chong Lei

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-14
https://doi.org/10.1186/s44158-026-00456-x