← brief for 2026-09-12 · Slowing decline

SGLT2 Inhibitors as Potential Agents for Prevention, Treatment, and/or Improved Recovery from Acute Kidney Injury.

Key takeaways

This review asks whether SGLT2 inhibitors, drugs that make the kidneys pass sugar out in urine, could prevent or speed recovery from sudden kidney failure (acute kidney injury). Sudden kidney failure matters because it can turn into long-term kidney disease or cause death. Most of the evidence it gathers comes from rat and mouse studies, not from patients. So this is a promising idea that has not been proven in people.

Who did this work

Sanchez-Vega D · Oskoui EP · Siskind LJ

Source

Article · PubMed, the drug frontier · 2026 Sep 13
https://pubmed.ncbi.nlm.nih.gov/42730809/