← brief for 2026-09-10 · Slowing decline

Plasma neurofilament light chain in type 2 diabetes: Associations with diabetic peripheral neuropathy, age, and renal function in a pilot cross-sectional study

Key takeaways

This small study measured a blood marker of nerve damage, called neurofilament light chain, in people with type 2 diabetes. It checked whether the marker tracks with nerve damage in the hands and feet, with older age, and with the kidney filtering rate (eGFR). Everything was measured at one point in time, so it can show a link, not proof of cause. The authors call it a pilot, meaning a first look that needs a bigger study to confirm.

Who did this work

Michaela Škorvanová (Comenius University Bratislava) · Andrea Izarik Verespejova (Comenius University Bratislava) · Jozef Hanes (Slovak Academy of Sciences) · Radovan Plášil (1 Military Clinical Hospital with Outpatient Clinic) · Natália Huňarová (Comenius University Bratislava) · Jakub Šofránko (Comenius University Bratislava) · Li-Sheng Chien (Comenius University Bratislava) · Martin Kolísek (Comenius University Bratislava)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-09
https://doi.org/10.1371/journal.pone.0357207