← brief for 2026-09-10 · Nutrition & lifestyle

Oral beta-D-glucan challenge to assess gut permeability in subjects receiving haemodialysis

Key takeaways

People on dialysis drank a sugar from yeast cell walls, beta-D-glucan, to test whether their gut lining leaks. If the sugar shows up in the blood, the gut wall is letting things through that it normally blocks. A leaky gut is one suspected source of the body-wide inflammation common in kidney failure. This was a small test of a measuring method, not a treatment trial, and the record here gives no participant count or results.

Who did this work

Oscar Swift (University of Hertfordshire) · Malcolm Finkelman (Cape Cod Hospital) · Yonglong Zhang (Cape Cod Hospital) · Eunice Doctolero (Lister Hospital) · Chadd Javier (Lister Hospital) · Mikky Gilbert (Lister Hospital) · Sivakumar Sridharan (University of Hertfordshire) · Ken Farrington (University of Hertfordshire) · E. Vilar (University of Hertfordshire)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-09
https://doi.org/10.1186/s12882-026-05340-y