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Efficacy of desmopressin in reducing post-procedural bleeding among chronic kidney disease patients: a systematic review and meta-analysis.

Article A Peer reviewed Meta-analysis or large trial

Key takeaways

Researchers pooled results from randomized trials, searching three medical databases through August 2025, to test whether the drug desmopressin cuts bleeding when people with chronic kidney disease have surgery or a procedure. Kidney disease makes the blood's clotting cells work poorly, so bleeding is a real risk. Desmopressin is already given for this, but doctors were not sure it worked. Pooling randomized trials is the strongest kind of evidence, so this gives a clearer answer than any single trial did.

Who did this work

Sirilertmekasakul C · Jindasakchai P · Sorasuchart S · Lertussavavivat T · Isaranuwatchai S

Source

Article · PubMed, CKD progression and prevention · 2026 Aug 26
https://pubmed.ncbi.nlm.nih.gov/42719070/