← brief for 2026-09-10 · Slowing decline

Birth characteristics and growth outcome in children with nephropathic cystinosis compared with other chronic kidney disease entities prior to kidney replacement therapy

Key takeaways

Researchers compared birth size and later growth in children with nephropathic cystinosis, a rare inherited disease that damages the kidneys, against children with other kinds of chronic kidney disease. All the children were still before dialysis or a transplant. The comparison points to differences in how these children grow, which matters because poor growth is a warning sign in childhood kidney disease. This is an observational study, so it shows a link and not proof of cause.

Who did this work

Katharina Schirmer (Medizinische Hochschule Hannover) · Malina Brügelmann (Medizinische Hochschule Hannover) · Laura Celine Brieger (Medizinische Hochschule Hannover) · Katharina Hohenfellner · Anja Büscher (Essen University Hospital) · Markus J. Kemper (Asklepios) · Kerstin Fröde (Medizinische Hochschule Hannover) · Nele Kanzelmeyer (Medizinische Hochschule Hannover) · Jun Oh (Kinderkrebs-Zentrum Hamburg) · Marcus Weitz (University Children's Hospital Tübingen) · Dominik Müller (Charité - Universitätsmedizin Berlin) · Lutz T. Weber (University Hospital Cologne)

Source

Paper · OpenAlex, CKD works · 2026-09-09
https://doi.org/10.1007/s00467-026-07534-w