← brief for 2026-09-08 · Slowing decline

Mycophenolate mofetil versus tacrolimus for maintenance of remission in children with frequently relapsing and steroid-dependent nephrotic syndrome: a pilot randomized controlled trial

Key takeaways

This was a small pilot randomized trial in children with nephrotic syndrome, a condition where the kidneys leak large amounts of protein into the urine and it keeps relapsing. It compared two drugs that calm the immune system, mycophenolate mofetil and tacrolimus, for keeping the disease quiet. A pilot trial is designed to test whether a bigger study is workable, not to settle which drug is better. The published record here does not give the number of children or the length of follow-up, so treat the comparison as preliminary.

Who did this work

Mohsina Naj (Institute of Post Graduate Medical Education and Research) · Koushik Bhattacharjee (Institute of Post Graduate Medical Education and Research) · Md Habibullah Sk (KPC Medical College and Hospital) · Mrinal Kanti Das (Institute of Post Graduate Medical Education and Research) · Arunansu Bandyopadhyay (Institute of Post Graduate Medical Education and Research) · Avijit Hazra (Institute of Post Graduate Medical Education and Research)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-07
https://doi.org/10.1007/s00467-026-07536-8