← brief for 2026-09-08 · Regeneration & devices

Macrophage heterogeneity in organ fibrosis in the era of single-cell omics.

Key takeaways

This is a review article about macrophages, a type of immune cell, and their role in organ scarring, which is called fibrosis. Scarring is the final common path that destroys kidney tissue, and there is still no treatment that reverses it. The authors describe what new single-cell tools have shown about the many different types of macrophages involved. It is a summary of other people's work, so there are no new results here.

Who did this work

Qiu W · Huang Y · Chen J · Chu C · Shen Q · Yan J

Source

Article · PubMed, fibrosis reversal · 2026 Sep 8
https://pubmed.ncbi.nlm.nih.gov/42709259/