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Effectiveness and Safety of Nefecon in Primary IgA Nephropathy Across Different Baseline Proteinuria Levels: A Real-World Study.

Key takeaways

Nefecon is a targeted form of the steroid budesonide, designed to act in the gut where the harmful antibodies in IgA nephropathy are made. In this real-world study, 28 patients were followed to see how well it worked and how safe it was, split by how much protein was leaking into their urine at the start. The patients were not randomly assigned and there was no comparison group, so this shows a link, not proof of cause. With only 28 people, the results are a first look rather than an answer.

Who did this work

Suolinge C · Dema C · Wu X · Jiang B · Lu C · Li J

Source

Article · PubMed, Reducing protein and albumin in urine · 2026 Sep 8
https://pubmed.ncbi.nlm.nih.gov/42709324/