← brief for 2026-09-08 · Slowing decline

Association between fibroblast growth factor 23 and coronary artery calcification in patients with chronic kidney disease: a meta-analysis

Paper C Peer reviewed Observational

Key takeaways

Researchers pooled many earlier studies of FGF23, a hormone that climbs when failing kidneys cannot clear phosphate, and calcium buildup in the heart arteries of people with kidney disease. Higher FGF23 levels went along with more calcium in those arteries, which is a marker of heart risk. Every pooled study was observational, so this shows a link, not proof that FGF23 causes the hardening.

Who did this work

Yi Yang (Jinshan Hospital of Fudan University) · Yingdan Zhao (Shanghai Jiao Tong University) · Hanqing Wang (Jinshan Hospital of Fudan University) · Xinxin Jiang (Jinshan Hospital of Fudan University) · Yi Xuan (Jinshan Hospital of Fudan University)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-07
https://doi.org/10.3389/fendo.2026.1900670