← brief for 2026-09-06 · Regeneration & devices

Sustained Low-Efficiency Dialysis Versus Intermittent Hemodialysis in Critically Ill Patients with Severe Acute Kidney Injury.

Article C Peer reviewed Observational

Key takeaways

This compared two ways of cleaning the blood in intensive care patients with severe sudden kidney failure: slow gentle dialysis run over many hours (SLED) and standard shorter hemodialysis. It covered 300 patients, 160 on the slow method and 140 on the standard one, and tracked deaths in intensive care, kidney recovery by discharge, length of stay, and kidney outcomes at 90 days. Patients were not randomly assigned to a method, so this shows a link between the method used and the outcomes, not proof that one method is better.

Who did this work

Wang X · Li J · Sun X · Zhu J · Yuan Z · Zhang X

Source

Article · PubMed, CKD severity and reversal · 2026 Sep 5
https://pubmed.ncbi.nlm.nih.gov/42700418/