← brief for 2026-09-06 · Transplant & xeno

Subcutaneous Daratumumab in Recurrent Posttransplant Focal Segmental Glomerulosclerosis: A Report of 2 Cases.

Key takeaways

Two people whose kidney disease came back after a transplant went into remission after getting daratumumab, a drug given as a shot under the skin. The disease is FSGS, a scarring of the kidney's tiny filters that leaks protein into the urine. One was a 51-year-old woman whose disease returned one month after her transplant, and she was also on plasma exchange every two weeks. This is a report on 2 patients with no comparison group, so it cannot show the drug is what worked.

Who did this work

Aleš Rigler A · Belčič Mikič T · Bošnjak M · Arnol M

Source

Article · PubMed, Reducing protein and albumin in urine · 2026 Jul 15
https://pubmed.ncbi.nlm.nih.gov/42698729/