← brief for 2026-09-04 · Slowing decline

Lithium-Induced Nephropathy in Bipolar Disorder: A Clinical Concern

Key takeaways

This is a review article on how lithium, a common long-term treatment for bipolar disorder, can damage the kidneys over years of use. The damage can include a drop in the kidney filtering rate (eGFR) and trouble concentrating urine, and it can build up quietly. The article gathers and discusses what is already known, so it reports no new results of its own. If you or a family member takes lithium, this is a reason to have kidney function checked on a schedule, not a reason to stop a medicine on your own.

Who did this work

Marta J (Setúbal Hospital Center , ,) · Magalhães M (Setúbal Hospital Center , ,) · Mendes S (Setúbal Hospital Center , ,) · Aleixo M (Setúbal Hospital Center , ,)

Source

Paper · Europe PMC, CKD · 2026-09-04
https://europepmc.org/article/PMC/PMC13444040