← brief for 2026-09-04 · Slowing decline

Systemic immune-inflammation index as a prognostic marker in heart failure with non-dialysis chronic kidney disease: a two-cohort derivation and validation study with head-to-head comparison against natriuretic peptides

Key takeaways

In people who have both heart failure and kidney disease but are not on dialysis, a simple inflammation score from a routine blood count predicted who did worse. The researchers built the score in one group of patients, then checked it in a second group, and compared it head to head with the standard heart blood test. This is an observational study, so the score marks higher risk. It does not prove that inflammation is what causes the harm.

Who did this work

Tao Chen (Jinan University) · Manyang Chen (Affiliated Hospital of Guizhou Medical University) · Mingzhu Hong (Affiliated Hospital of Guangdong Medical College Hospital) · Minghui Zhu (Affiliated Hospital of Guangdong Medical College Hospital) · Can Chen (Jinan University)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-03
https://doi.org/10.3389/fcvm.2026.1928233