← brief for 2026-09-04 · Slowing decline

Serum and Urine Metabolite Profiling Combined With Network Pharmacology to Predict the Renoprotective Mechanism of Huangkui Capsule Against Acute Kidney Injury.

Key takeaways

Huangkui capsule is a plant extract used in China for long-term kidney disease. Researchers gave it to rats, measured which of its compounds showed up in blood and urine, and used computer analysis to predict how those compounds might protect against sudden kidney injury. This was done in rats and on computers, not in people. There is no evidence here that it helps a person with kidney injury.

Who did this work

Shi JJ (Department of Clinical Pharmacology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.) · Liao JC (Department of Clinical Pharmacology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.) · Qiao SM (Department of Clinical Pharmacology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.) · Tang YT (Department of Clinical Pharmacology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.) · Zou JD (Department of Clinical Pharmacology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.) · Li CY (Department of Clinical Pharmacology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.)

Source

Paper · Europe PMC, CKD · 2026-09-01
https://doi.org/10.1002/bmc.70557