← brief for 2026-09-04 · Slowing decline

Long-term outcomes associated with continued use of ARBs versus CCBs in older adults: a landmark cohort study.

Key takeaways

This study compared two kinds of blood pressure drugs in older adults in Japan who had already been on treatment for a long time: ARBs, the class usually chosen to protect kidneys, and calcium channel blockers. It followed people aged 65 and over using insurance claims and health checkup records. Because it looks back at records instead of assigning treatment, it can show a link between drug choice and later outcomes, not proof that one drug caused them. The outcome numbers are not in the text available here.

Who did this work

Noma H (Department of Interdisciplinary Statistical Mathematics, The Institute of Statistical Mathematics, Tokyo, Japan. [email protected].) · Sunada H (Advanced Medicine, Innovation and Clinical Research Center, Tottori University Hospital, Tottori, Japan.) · Yamazaki H (Section of Clinical Epidemiology, Department of Community Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.) · Oda F (Department of Health Care Administration and Management, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.) · Maeda M (Department of Health Care Administration and Management, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.) · Fukuda H (Department of Health Care Administration and Management, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan.)

Source

Paper · Europe PMC, CKD · 2026-09-03
https://doi.org/10.1038/s41440-026-02793-4