← brief for 2026-09-04 · Slowing decline

Insulin resistance and uric acid-related metabolic disturbances jointly identify individuals at high risk of advanced cardiovascular-kidney-metabolic syndrome: a population-based study

Paper C Peer reviewed Observational

Key takeaways

This study checked two things in a large group of adults: how well their bodies respond to insulin, and their uric acid level. People who had trouble with both were far more likely to have advanced disease of the heart, kidneys, and metabolism. This is an observational study, so it shows a link, not proof that one causes the other. It does not test whether fixing either measure protects the kidneys.

Who did this work

Shengzhu Huang (Guangxi Medical University) · Jingwei Lin (Guangxi Medical University) · Lingyu Ye (Guangxi Medical University) · Fuxiang Fang (Guangxi Medical University) · Yezhou Wu (Guangxi Medical University) · Xuefang Liang (Guangxi Medical University) · Junwu Ran (Guangxi Medical University) · Zhuokun Wei (Guangxi Medical University) · Fuhua Hu (Guangxi Medical University) · Yibi Lan (Guangxi Medical University) · Wen Zheng (Guangxi Medical University) · Mingli Li (Guangxi Medical University)

Source

Paper · OpenAlex, CKD works · 2026-09-03
https://doi.org/10.3389/fnut.2026.1933816