← brief for 2026-09-04 · Slowing decline

Elevated urinary angiotensinogen excretion links incidence of chronic kidney disease among community-dwelling population: The Aging Kidney Study.

Article C Peer reviewed Observational

Key takeaways

Researchers followed adults in the community who did not have kidney disease and measured a protein called angiotensinogen in their urine. Higher levels came before new cases of chronic kidney disease, which points to an overactive hormone system inside the kidney as a possible early warning sign. This was an observational study, so it shows a link, not proof that the protein causes the damage. This record does not give the number of people followed or for how long.

Who did this work

Yoshikoshi S · Kosaki K · Mori S · Maeda S · Kuro-O M · Yamagata K

Source

Article · PubMed, CKD progression and prevention · 2026 Aug 13
https://pubmed.ncbi.nlm.nih.gov/42695380/