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Bone turnover biomarkers and semi-quantitative bone histomorphometry in chronic kidney disease: Comparison between patients with and without fractures.

Article C Peer reviewed Observational

Key takeaways

People with chronic kidney disease break bones more often than their bone density scores predict. This study in India compared routine blood tests of bone turnover, meaning how fast bone is broken down and rebuilt, against actual bone samples viewed under a microscope, in patients with and without fractures. The goal was to see whether cheap blood tests can stand in for a bone biopsy where biopsies are hard to get. It compares groups rather than testing a treatment, so it can show links, not cause.

Who did this work

Sharma S · Sujir P · Rajasekharan P · Kotian P · Bhupal M · Sudhanva GN · Parimi K

Source

Article · PubMed, Nutritional supplements and CKD · 2026 Sep 2
https://pubmed.ncbi.nlm.nih.gov/42694476/