← brief for 2026-09-04 · Regeneration & devices

Alignment of Micrometer-Scale Electrospun Fibers Does Not Enhance Performance of Primary Human Renal Proximal Tubular Epithelial Cells.

Key takeaways

Researchers grew human kidney tubule cells on very thin man made fibers, testing whether lining the fibers up in one direction helped. It did not: aligned fibers worked no better than random ones. The goal is a lab grown kidney that filters and also does the kidney's other jobs, which dialysis cannot do. This was done with cells in the lab, not in people.

Who did this work

Vermue IM · van Dijk CGM · Chrifi I · Appels Y · van Meijeren J · Terhaard B · Kasaiyan N · Verhaar MC · Cheng C

Source

Article · PubMed, organoids & devices · 2026 Sep
https://pubmed.ncbi.nlm.nih.gov/42693694/