← brief for 2026-08-30 · Slowing decline

Role of fibroblast growth factor 23 in predicting CKD progression and prognosis: a systematic review and meta-analysis.

Article A Peer reviewed Meta-analysis or large trial

Key takeaways

A large review of 12 studies with over 21,000 people found that high levels of a blood protein called FGF-23 strongly predict faster kidney decline, kidney failure, heart problems, and early death — even after adjusting for other risk factors. This suggests FGF-23 could be a useful tool to spot high-risk patients early.

Who did this work

Hsu JW · Wang HP · Chiang TI

Source

Article · PubMed, CKD progression · 2026 Aug 24
https://pubmed.ncbi.nlm.nih.gov/42668972/