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Metabolomic Signatures of Inflammation in Chronic Kidney Disease.

Key takeaways

Researchers measured 718 different chemicals in the blood of people with kidney disease and checked which ones tracked with signs of inflammation. They used three long-running study groups: AASK, ARIC, and the Boston Kidney Biopsy Cohort. Inflammation goes along with faster kidney decline, heart problems, and earlier death, so these chemical patterns may help explain why. This is observational, so it shows a link, not proof that these chemicals cause the harm.

Who did this work

Chen TK · Surapaneni AL · Estrella MM · Appel LJ · Obeid W · Parikh CR · Rooney MR · Yu B · Rhee EP · Schmidt IM · Waikar SS · Grams ME

Source

Article · PubMed, CKD progression and prevention · 2026 Jun 27
https://pubmed.ncbi.nlm.nih.gov/42668601/